MAO-B-IN-13

CAS: 2105918-34-9 F: C18H19NO3 W: 297.35

MAO-B-IN-13 (compound 12a) is a highly potent, reversible and blood-brain barrier (BBB) penetrant MAO-B inhibitor with a

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Bioactivity	MAO-B-IN-13 (compound 12a) is a highly potent, reversible and blood-brain barrier (BBB) penetrant MAO-B inhibitor with an IC50 value of 10 nM. MAO-B-IN-13 has neuroprotective and antioxidant activity. MAO-B-IN-13 can be used for researching Parkinson’s disease[1].
Invitro	MAO-B-IN-13 (compound 12a) (1 μM, 10 μM and 50 μM; 48 hours) has neuroprotective effect on H2O2-induced PC-12 cell injury[1].
Name	MAO-B-IN-13
CAS	2105918-34-9
Formula	C18H19NO3
Molar Mass	297.35
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Li W, et al. Pyridoxine-resveratrol hybrids as novel inhibitors of MAO-B with antioxidant and neuroprotective activities for the treatment of Parkinson's disease. Bioorg Chem. 2020 Apr;97:103707.