Bioactivity | MAGL-IN-8 (compound 13) is a reversible monoacylglycerol lipase (MAGL) inhibitor, with an IC50 of 2.5 ± 0.4 nM for hMAGL[1]. |
Target | IC50: 2.5 ± 0.4 μM (hMAGL) |
Name | MAGL-IN-8 |
Formula | C25H23F3N2O2S |
Molar Mass | 472.52 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Granchi C, et al. Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors. Eur J Med Chem. 2021 Jan 1;209:112857. |