Bioactivity | M3554 is a novel anti-GD2 ADC designed based on humanized ch14.18 anti-GD2 antibody and has anti-tumor activity. The cytotoxicity of M3554 against the GD2-positive neuroblastoma cell line CHP134 was in the subnanomolar IC50 range. |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Amendt C, et al. Abstract ND08: M3554, a novel anti-GD2 antibody drug conjugate[J]. Cancer Research, 2024, 84(7_Supplement): ND08-ND08. |