| Bioactivity | M199 is a potent TLR3/9 signaling inhibitor. M199 induces secretion of IL-6, IL-8 and TNFα in human PBMCs. M199 is used as a selective inducer of the immune response[1]. |
| CAS | 1051933-86-8 |
| Formula | C17H17N3O |
| Molar Mass | 279.34 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Natalija Knežević Teofilović, et al. 1-ethyl-3-(6-methylphenanthridine-8-il) urea modulates TLR3/9 activation and induces selective pro-inflammatory cytokine expression in vitro. Bioorg Med Chem Lett. 2017 Apr 1;27(7):1530-1537. |