| Bioactivity | M133 peptide is a coronavirus-specific CD4 T cell epitope. M133 peptide is immunodominant in mice infected with the neurotropic coronavirus (the JHM strain of mouse hepatitis virus). M133 peptide forms a complex with MHC II molecules, which is recognized by specific TCRs, thereby activating CD4 T cells[1]. |
| Sequence | Thr-Val-Tyr-Val-Arg-Pro-Ile-Ile-Glu-Asp-Tyr-His-Thr-Leu-Thr |
| Shortening | TVYVRPIIEDYHTLT |
| Formula | C84H130N20O25 |
| Molar Mass | 1820.05 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhao J, et al. Development of transgenic mice expressing a coronavirus-specific public CD4 T cell receptor. J Immunol Methods. 2013 Oct 31;396(1-2):56-64. |