| Bioactivity | M084 hydrochloride is a TRPC4/5 channel blocker, with IC50 values of 10.3 μM and 8.2 μM, respectively. M084 hydrochloride has antidepressant and anxiolytic effects[1][2]. |
| Name | M084 hydrochloride |
| CAS | 1992047-63-8 |
| Formula | C11H16ClN3 |
| Molar Mass | 225.72 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yang LP, et al. Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice. PLoS One. 2015 Aug 28;10(8):e0136255. [2]. Zhu Y, et al. Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels. Br J Pharmacol. 2015 Jul;172(14):3495-509. |