| Bioactivity | Lyso-PAF C-18 is an intermediate for the synthesis of C18-PAF (HY-130345). It has an easily substituted "Lyso-PAF" structure and is easy to purify and has high yield. C18-PAF is a ligand for platelet-activating factor and PAF G protein-coupled receptor (PAFR) and has renovasodilator properties and antihypertensive lipid properties[1][2]. |
| Name | Lyso-PAF C-18 |
| CAS | 74430-89-0 |
| Formula | C26H56NO6P |
| Molar Mass | 509.70 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Heymans F, et al. New total synthesis and high resolution 1H NMR spectrum of platelet-activating factor, its enantiomer and racemic mixtures[J]. Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism, 1981, 666(2): 230-237. [2]. Vargaftig BB, et al. Background and present status of research on platelet-activating factor (PAF-acether). Ann N Y Acad Sci. 1981;370:119-37. |