Bioactivity | Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg is a substrate of protein kinase C from EGF receptor. Lys-Arg-Thr-Leu-Arg-Arg can be used to determine the activity of protein kinase C[1]. |
Invitro | Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR; 0.5 mg/mL; 20 min; WI-38 fibroblasts) increases the activity of a membrane-bound Ca2+-inhibited protein kinase and induces autophosphorylation to determine the activity of protein kinase C[1]. |
Name | Lys-Arg-Thr-Leu-Arg-Arg |
CAS | 121284-21-7 |
Shortening | KRTLRR |
Formula | C34H68N16O8 |
Molar Mass | 829.01 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Davis RJ, et, al. Stimulation of epidermal growth factor receptor threonine 654 phosphorylation by platelet-derived growth factor in protein kinase C-deficient human fibroblasts. J Biol Chem. 1987 May 15;262(14):6832-41. |