| Bioactivity | Luteinizing Hormone Releasing Hormone (LH-RH), salmon (Salmon GnRH) is the hypophysiotropic decapeptide synthesized in the hypothalamus that plays a crucial role in the control of reproductive functions. | ||||||
| Invitro | Luteinizing hormone-releasing hormone (LHRH) is the key hormone in the control of reproductive functions.LHRH acts as an antimitogenic factor through the activation of the Gi-cAMP intracellular signaling pathway. LHRH might act as an inhibitory factor on both cell proliferation and metastatic behavior in melanoma cells[1]. The hypothalamic decapeptide luteinizing hormone-releasing hormone (LHRH) plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn promote gonadal functions and regulate sex steroid secretion. The effects of LHRH are mediated by high-affinity G protein-coupled LHRH-receptor (LHRH-R) on pituitary gonadotropes. The responses to LHRH vary under different conditions and critically depend on the regimens of administration and doses delivered to gonadotrope cells[2]. | ||||||
| Name | Luteinizing Hormone Releasing Hormone (LH-RH), salmon | ||||||
| CAS | 86073-88-3 | ||||||
| Sequence | {Glp}-His-Trp-Ser-Tyr-Gly-Trp-Leu-Pro-Gly-NH2 | ||||||
| Shortening | {Glp}-HWSYGWLPG-NH2 | ||||||
| Formula | C60H73N15O13 | ||||||
| Molar Mass | 1212.31 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
Luteinizing Hormone Releasing Hormone (LH-RH), salmon
CAS: 86073-88-3 F: C60H73N15O13 W: 1212.31
Luteinizing Hormone Releasing Hormone (LH-RH), salmon (Salmon GnRH) is the hypophysiotropic decapeptide synthesized in t
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