Bioactivity | Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist, used for treatment of chronic liver disease. | ||||||||||||
Invitro | Lusutrombopag acts selectively on the human TPO receptor and activates signal transduction pathways that promote the proliferation and differentiation of bone marrow cells into megakaryocytes, thereby increasing platelet levels[1]. | ||||||||||||
Name | Lusutrombopag | ||||||||||||
CAS | 1110766-97-6 | ||||||||||||
Formula | C29H32Cl2N2O5S | ||||||||||||
Molar Mass | 591.55 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Kim ES, et al. Lusutrombopag: First Global Approval. Drugs. 2016 Jan;76(1):155-8. |