Bioactivity | Luotonin F is an alkaloid found in the aerial parts of the P. nigellastrum Bunge. Luotonin F shows cytotoxic activity against mouse leukemia P-388 cells by inhibiting human topoisomerase II[1][2]. |
Invitro | Luotonin F 对小鼠白血病 P-388 细胞具有细胞毒活性 (IC50: 2.3 μg/mL)[1]。Luotonin F (25 μM) 抑制人拓扑异构酶 II 活性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Luotonin F 相关抗体: |
CAS | 244616-85-1 |
Formula | C18H11N3O2 |
Molar Mass | 301.30 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Liang JL, et al. Recent advances in the studies on luotonins. Molecules. 2011 Jun 14;16(6):4861-83. [2]. Ma Z, et al. Novel quinazoline-quinoline alkaloids with cytotoxic and DNA topoisomerase II inhibitory activities. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1193-6. |