Bioactivity | Lunasin is a bioactive peptide with antioxidant, anti-inflammatory, anticancer and anti-aging properties. Lunasin can be isolated from soybean. Lunasin also has an epigenetic mechanism of action associated with histone acetylation. Lunasin can be internalized into cells and inhibit Oncosphere formation in cancer cells[1]. |
Invitro | Lunasin 由 4 个部分组成,其中包含有天冬氨酸 (D) 的尾部和 RGD 基序。RGD 基序决定了 Lunasin 内化到细胞中及其抗转化作用,并与 Lunasin 诱导的黑素瘤细胞系 A375 ALDHhigh 中甲蚴形成的抑制有关[1]。 |
Name | Lunasin |
CAS | 496823-34-8 |
Sequence | Ser-Lys-Trp-Gln-His-Gln-Gln-Asp-Ser-Cys-Arg-Lys-Gln-Leu-Gln-Gly-Val-Asn-Leu-Thr-Pro-Cys-Glu-Lys-His-Ile-Met-Glu-Lys-Ile-Gln-Gly-Arg-Gly-Asp-Asp-Asp-Asp-Asp-Asp-Asp-Asp-Asp |
Shortening | SKWQHQQDSCRKQLQGVNLTPCEKHIMEKIQGRGDDDDDDDDD |
Formula | C204H321N65O78S3 |
Molar Mass | 5028.32 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Alves de Souza SM, et al. Lunasin as a Promising Plant-Derived Peptide for Cancer Therapy. Int J Mol Sci. 2022 Aug 23;23(17):9548. |