| Bioactivity | Lubeluzole (dihydrochloride) is a neuroprotective agent which blockades neuronal voltage-gated sodium channels. Lubeluzole (dihydrochloride) also produces both tonic and block of cardiac sodium channels. Lubeluzole (dihydrochloride) is promising for research of antiarrhythmic agents[1][2]. |
| CAS | 144665-09-8 |
| Formula | C22H27Cl2F2N3O2S |
| Molar Mass | 506.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Le Grand B, et al. Study of the interaction of lubeluzole with cardiac sodium channels. J Cardiovasc Pharmacol. 2003 Nov;42(5):581-7. [2]. Le Grand B, et al. Lubeluzole-induced prolongation of cardiac action potential in rabbit Purkinje fibres. Fundam Clin Pharmacol. 2000 Mar-Apr;14(2):159-62. |
Lubeluzole dihydrochloride
CAS: 144665-09-8 F: C22H27Cl2F2N3O2S W: 506.44
Lubeluzole (dihydrochloride) is a neuroprotective agent which blockades neuronal voltage-gated sodium channels. Lubeluzo
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