| Bioactivity | Lu AF11205 is a mGlu5 receptor positive allosteric modulator with activity modulating mGlu5 receptor activity. Optimization of Lu AF11205 resulted in a series of potent fused thiazole analogs whose structures and activities were influenced by substituents and which could affect receptor function in cell lines expressing mGlu5 receptors. |
| CAS | 1290133-16-2 |
| Formula | C17H16N2OS |
| Molar Mass | 296.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Fused thiazolyl alkynes as potent mGlu5 receptor positive allosteric modulators |