| Bioactivity | Lp-PLA2-IN-1 is a potent Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2-IN-1 has the potential for atherosclerosis, Alzheimer's disease research[1]. | ||||||||||||
| Invitro | Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2 travels with low-density lipoprotein (LDL) and rapidly cleaves oxidized phosphatidylcholine molecules derived from the oxidation of LDL[1] | ||||||||||||
| Name | Lp-PLA2-IN-1 | ||||||||||||
| CAS | 1420367-28-7 | ||||||||||||
| Formula | C21H17F5N4O3 | ||||||||||||
| Molar Mass | 468.38 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Zehong Wan, et al. Bicyclic pyrimidone compounds. WO2013014185A1. |