| Bioactivity | Losartan Carboxylic Acid (Standard) is the analytical standard of Losartan Carboxylic Acid. This product is intended for research and analytical applications. Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure[4]. |
| CAS | 124750-92-1 |
| Formula | C22H21ClN6O2 |
| Molar Mass | 436.89 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Losartan Carboxylic Acid (Standard)
CAS: 124750-92-1 F: C22H21ClN6O2 W: 436.89
Losartan Carboxylic Acid (Standard) is the analytical standard of Losartan Carboxylic Acid. This product is intended for
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This product is for research use only, not for human use. We do not sell to patients.