PeptideDB

Lofexidine

CAS: 31036-80-3 F: C11H12Cl2N2O W: 259.13

Lofexidine is a selective α2-receptor agonist, commonly used to alleviate the physical symptoms of heroin and other typ
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Lofexidine is a selective α2-receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal[1][2].
Target α2-receptor.
Name Lofexidine
CAS 31036-80-3
Formula C11H12Cl2N2O
Molar Mass 259.13
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Vartak AP, et al. The preclinical discovery of lofexidine for the treatment of opiate addiction. Expert Opin Drug Discov. 2014 Nov;9(11):1371-7. [2]. Gish EC, et al. Lofexidine, an {alpha}2-receptor agonist for opioid detoxification. Ann Pharmacother. 2010 Feb;44(2):343-51.