PeptideDB

Lobenzarit disodium

CAS: 64808-48-6 F: C14H8ClNNa2O4 W: 335.65

Lobenzarit disodium (CCA) is an anti-arthritic and anti-oxidative agent.
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Lobenzarit disodium (CCA) is an anti-arthritic and anti-oxidative agent[1].
Invitro Lobenzarit disodium (CCA) 抑制活性氧诱导的化学发光,IC50 为 1.6 μM[1]。Lobenzarit disodium (0.3-300 μM) 抑制过氧化脂质生成和紫外线照射诱导的 IgG 改变[1]。
In Vivo Lobenzarit disodium (CCA; 10 and 50 mg/kg; i.p.; daily for 7 days) 通过激活抑制性 T 淋巴细胞发挥其抗关节炎作用[2]。 Animal Model:
Name Lobenzarit disodium
CAS 64808-48-6
Formula C14H8ClNNa2O4
Molar Mass 335.65
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Cynshi O, et al. Anti-oxidative profile of lobenzarit disodium (CCA). Biochem Pharmacol. 1990 Nov 1;40(9):2117-22. [2]. Yoshiyuki Ohsugi, et al. Therapeutic effect of lobenzarit disodium (CCA) on adjuvant arthritis in rats: Short-lived suppressor T lymphocytes might be involved. 1984 Apr 3; 243-245.