Bioactivity | Lipoxygenin is a non-redox 5-lipoxygenase (5-LO) inhibitor with an IC50 of 5 μM. Lipoxygenin modulates the β-catenin-5-LO complex, inducing a decrease in β-catenin and 5-LO levels in the nucleus[1]. |
CAS | 2247911-68-6 |
Formula | C24H22N2O4 |
Molar Mass | 402.44 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Brand S, et al. Combined Proteomic and In Silico Target Identification Reveal a Role for 5-Lipoxygenase in Developmental Signaling Pathways. Cell Chem Biol. 2018 Sep 20;25(9):1095-1106.e23. |