| Bioactivity | Liothyronine sodium hydrate is an active form of thyroid hormone. Liothyronine sodium hydrate is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1][2][3]. |
| Invitro | Liothyronine (T3, 100 nM) sodium hydrate stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed[1]. Liothyronine sodium hydrate binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine sodium hydrate promotes growth, induces differentiation and regualtes metabolic effects[2]. |
| Name | Liothyronine sodium hydrate |
| CAS | 345957-19-9 |
| Formula | C15H12I3NO4.xH2O.Na |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |