| Bioactivity | Linoleic Acid-d5 is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism[1][2]. | |||||||||
| Invitro | 氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。 氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。 | |||||||||
| Name | Linoleic acid-d5 | |||||||||
| CAS | 1169764-58-2 | |||||||||
| Formula | C18H27D5O2 | |||||||||
| Molar Mass | 285.48 | |||||||||
| Appearance | Liquid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Jay Whelan. Linoleic Acid. Adv Nutr. 2013 May; 4(3): 311–312. |
Linoleic acid-d5
CAS: 1169764-58-2 F: C18H27D5O2 W: 285.48
Linoleic Acid-d5 is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant
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