Bioactivity | Linderaspirone A is a natural compound that can be isolated from the roots of Lindera aggregate. Linderaspirone A shows significant inhibitory effects on the production of prostaglandin E2 (PGE2),TNF-α, and IL-6 [1][2]. |
Invitro | Linderaspirone A also inhibits the expression of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2), which are pro-inflammatory proteins, and the activation of nuclear factor κB (NF-κB) [2]. |
Name | Linderaspirone A |
CAS | 1235126-46-1 |
Formula | C34H32O10 |
Molar Mass | 600.61 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Lin Chen, et al. Lindera cyclopentenedione intermediates from the roots of Lindera aggregate. RSC Adv. 2018 May 16;8(32):17898-17904. [2]. Chi-Su Yoon, et al. Effects of Compounds Isolated from Lindera erythrocarpa on Anti-Inflammatory and Anti-Neuroinflammatory Action in BV2 Microglia and RAW264.7 Macrophage. Int J Mol Sci. 2022 Jun 27;23(13):7122. |