| Bioactivity | Linaclotide acetate is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation. |
| CAS | 851199-60-5 |
| Sequence | Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr (disulfide bridge: Cys1-Cys6; Cys2-Cys10; Cys5-Cys13) |
| Shortening | CCEYCCNPACTGCY (disulfide bridge: Cys1-Cys6; Cys2-Cys10; Cys5-Cys13) |
| Formula | C61H83N15O23S6 |
| Molar Mass | 1586.79 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bryant AP, et al. Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract. Life Sci. 2010 May 8;86(19-20):760-5. [2]. Love BL, et al. Linaclotide: a novel agent for chronic constipation and irritable bowel syndrome. Am J Health Syst Pharm. 2014 Jul 1;71(13):1081-91. |
Linaclotide acetate
CAS: 851199-60-5 F: C61H83N15O23S6 W: 1586.79
Linaclotide acetate is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-p
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.