| Bioactivity | Lin28-let-7 antagonist 1 (compound 1632) is a potent antagonist of Lin28/pre-let-7 interaction. Lin28-let-7 antagonist 1 inhibits Lin28A binding to pre-let-7a-2, with an IC50 of 8 μM. Lin28-let-7 antagonist 1 inhibits proliferation in human cancer cells[1]. |
| Name | Lin28-let-7 antagonist 1 |
| CAS | 108825-65-6 |
| Formula | C15H15N5O |
| Molar Mass | 281.31 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Roos M, et al. A Small-Molecule Inhibitor of Lin28. ACS Chem Biol. 2016 Oct 21;11(10):2773-2781. |
Lin28-let-7 antagonist 1
CAS: 108825-65-6 F: C15H15N5O W: 281.31
Lin28-let-7 antagonist 1 (compound 1632) is a potent antagonist of Lin28/pre-let-7 interaction. Lin28-let-7 antagonist 1
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