Bioactivity | Limonene-13C,d2 is 13C and deuterated labeled Limonene (HY-N0544)[1]. Limonene is a monoterpene in citrus peel oil. A popular disinfectant and food preservative. Antimicrobial activities[2]. Anti-proliferative activities[3]. Antioxidant and anti-inflammatory effect[4]. |
Target | Bacterial |
Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。 0 --> Limonene-13C,d2 相关抗体: |
Name | Limonene-13C,d2 |
CAS | 1351625-27-8 |
Formula | C913CH14D2 |
Molar Mass | 139.24 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Chubukov V, et al. Acute Limonene Toxicity in Escherichia coli Is Caused by Limonene Hydroperoxide and Alleviated by a Point Mutation in Alkyl Hydroperoxidase AhpC. Appl Environ Microbiol. 2015 Jul;81(14):4690-6. [3]. Roberto D, et al. Antioxidant activity of limonene on normal murine lymphocytes: relation to H2O2 modulation and cell proliferation. Basic Clin Pharmacol Toxicol. 2010 Jan;106(1):38-44. [4]. de Souza MC, et al. Gastroprotective effect of limonene in rats: Influence on oxidative stress, inflammation and gene expression. Phytomedicine. 2018 Sep 4;53:37-42. |