| Bioactivity | Licofelone (ML-3000) is a dual COX/5-lipoxygenase (5-LOX) inhibitor (IC50=0.21/0.18 μM, respectively) for the treatment of osteoarthritis. Licofelone exerts anti-inflammatory and anti-proliferative effects. Licofelone induces apoptosis, and decreases the production of proinflammatory leukotrienes and prostaglandins[1][2][3]. | |||||||||
| Invitro | The IC50s of human thrombocyte COX and human 5-LO are 0.16 µM and 0.23 µM, respectively[3]. | |||||||||
| Name | Licofelone | |||||||||
| CAS | 156897-06-2 | |||||||||
| Formula | C23H22ClNO2 | |||||||||
| Molar Mass | 379.88 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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Licofelone
CAS: 156897-06-2 F: C23H22ClNO2 W: 379.88
Licofelone (ML-3000) is a dual COX/5-lipoxygenase (5-LOX) inhibitor (IC50=0.21/0.18 μM, respectively) for the treatment
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