Bioactivity | Lib2-1, a macrocyclic peptide, is an IL-17C/IL-17RE interaction inhibitor. Lib2-1 can be used for autoimmune and inflammatory diseases research[1]. |
Name | Lib2-1 |
CAS | 2983116-47-6 |
Sequence | Ac-Tyr-His-Ile-Tyr-Tyr-Ala-Ser-Leu-Tyr-Gly-Asp-Leu-Gly-Cys-Gly-NH2 (Thioether bond between: Tyr1-Cys15) |
Shortening | Ac-YHIYYASLYGDLGCG-NH2 (Thioether bond between: Tyr1-Cys15) |
Formula | C81H108N18O23S |
Molar Mass | 1733.90 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Silong Zhai, et al. PepScaf: Harnessing Machine Learning with In Vitro Selection toward De Novo Macrocyclic Peptides against IL-17C/IL-17RE Interaction. J Med Chem. 2023 Aug 24;66(16):11187-11200. |