PeptideDB

Levomefolic acid

CAS: 31690-09-2 F: C20H25N7O6 W: 459.46

Levomefolic acid (5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most
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Bioactivity Levomefolic acid (5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements[1][2].
Invitro Levomefolic acid (5-MTHF) shows interaction with residues Glu406, Ile 418, Lys417 and Tyr453, of which Lys 417 and Tyr 453 play a strong physiological role in the interaction between S1 and ACE and may act as a potential inhibitor of the S1:ACE2 interaction of the SARS-CoV-2 virus[1].Levomefolic acid (5-MTHF) (50 nM, 72 h) increases intracellular folate metabolite activity by 7-fold better than folic acid by 2-fold in human lymphoblastoid cell line (LCL), and is a good folic acid supplement[2].
Name Levomefolic acid
CAS 31690-09-2
Formula C20H25N7O6
Molar Mass 459.46
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month