| Bioactivity | Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2][3]. |
| Invitro | Leukotriene B4 induces recruitment and activation of neutrophils, monocytes and eosinophils. It also stimulates the production of a number of proinflammatory cytokines and mediators indicating an ability to augment and prolong tissue inflammation[2].Leukotriene B4 is a pro-inflammatory mediator synthesised in myeloid cells from arachidonic acid[2]. |
| Name | Leukotriene B4 |
| CAS | 71160-24-2 |
| Formula | C20H32O4 |
| Molar Mass | 336.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Solution, -20°C, 2 years |
Leukotriene B4
CAS: 71160-24-2 F: C20H32O4 W: 336.47
Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved i
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