Leukotriene B4 ethanolamide

CAS: 877459-63-7 F: C22H37NO4 W: 379.53

Leukotriene B4 ethanolamide (LTB4 ethanolamide) is an antagonist and a partial agonist for Leukotriene B4 (LTB4) recepto

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Bioactivity	Leukotriene B4 ethanolamide (LTB4 ethanolamide) is an antagonist and a partial agonist for Leukotriene B4 (LTB4) receptor 1 (BLTR1). Leukotriene B4 ethanolamide ameliorates the tumor progression, which is only asscociated with inflammation[1][2].
Invitro	Leukotriene B4 ethanolamide 可抑制豚鼠离体肺实质中 LTB 4 的收缩作用，Kb 为 7.28 nM[1]。Leukotriene B4 ethanolamide (1 μM) 作为 PMN 细胞中 BLT 受体的部分激动剂，诱导 PMN 迁移，pEC50 为 7[2]。Leukotriene B4 ethanolamide (1 μM) 刺激 TRPV1 表达的大鼠 CHO 细胞中 Ca2+ 释放，pEC50 为 7.28[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Leukotriene B4 ethanolamide 相关抗体: Cell Migration Assay [2] Cell Line:
In Vivo	Leukotriene B4 ethanolamide (100 nM/mouse/day，皮下注射，共 5 天) 可抑制 C57BL/6 小鼠模型中与炎症相关的肿瘤进展[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
CAS	877459-63-7
Formula	C22H37NO4
Molar Mass	379.53
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. McHugh D, et al., Novel compounds that interact with both leukotriene B4 receptors and vanilloid TRPV1 receptors. J Pharmacol Exp Ther. 2006 Feb;316(2):955-65. [2]. Bachi AL, et al., Leukotriene B4 creates a favorable microenvironment for murine melanoma growth. Mol Cancer Res. 2009 Sep;7(9):1417-24.

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