Bioactivity | Leucomycin A13 is a macrolide antibiotic and a component of the leucomycin complex originally isolated from S. kitasatoensis. It is active against B. subtilis, S. aureus, M. luteus, and E. coli with MIC values of 0.16, 0.16, 0.08 and >10 μg/mL, respectively. It binds to ribosomes with an IC50 value of 1.2 μM in a radioligand binding assay. |
CAS | 78897-52-6 |
Formula | C41H69NO14 |
Molar Mass | 799.98 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Tanaka, et al. Quantitative structure-activity relationships of O-acyl derivatives of leucomycin for antimicrobial and ribosome-binding activities. Chem. Pharm. Bull. (Tokyo) 33(7), 2803-2808 (1985). |