Bioactivity | Leucettamol A is an inhibitor of Ubc13-Uev1A interaction, with an IC50 of 50 μg/mL. Leucettamol A can be isolated from a marine sponge, Leucetta aff. Microrhaphis[1]. |
Invitro | Leucettamol A 能通过阻止异二聚体 E2 复合物 Ubc13/Uev1A 的形成来抑制其活性[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Leucettamol A 相关抗体: |
CAS | 151124-32-2 |
Formula | C30H52N2O2 |
Molar Mass | 472.75 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sachiko Tsukamoto, et al. Leucettamol A: a new inhibitor of Ubc13-Uev1A interaction isolated from a marine sponge, Leucetta aff. Microrhaphis. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6319-20. [2]. Kimberli M Helms, et al. Vitexin inhibits polyubiquitin synthesis by the ubiquitin-conjugating enzyme E2-25K. Nat Prod Commun. 2011 Oct;6(10):1411-6. |