| Bioactivity | Lavendustin A (RG-14355) is a potent, selective and ATP-competitive inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase, with an IC50 of 11 nM. Lavendustin A does not inhibit protein kinase A or C. Lavendustin A can suppress VEGF-induced angiogenesis[1][2]. |
| Invitro | Lavendustin A (5-50μM) 剂量依赖性地抑制卵巢分散培养物中的孕酮产生[3]。 |
| Name | Lavendustin A |
| CAS | 125697-92-9 |
| Formula | C21H19NO6 |
| Molar Mass | 381.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
Lavendustin A
CAS: 125697-92-9 F: C21H19NO6 W: 381.38
Lavendustin A (RG-14355) is a potent, selective and ATP-competitive inhibitor of epidermal growth factor receptor (EGFR)
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