| Bioactivity | LasR-IN-4 is a potent LasR inhibitor. LasR-IN-4 can inhibit Pseudomonas aeruginosa and its biofilm formation, pyocyanin production, and rhamnolipids production[1]. |
| Target | MIC: 56.25 μg/mL (P. aeruginosa) |
| Invitro | LasR-IN-4 (compound 3d) has inhibitory activity against P. aeruginosa with MIC of 56.25 μg/mL, and inhibits biofilm formation, pyocyanin production, and rhamnolipids production of 71.70%, 68.70% and 54.00%, respectively[1]. |
| Name | LasR-IN-4 |
| CAS | 183488-96-2 |
| Formula | C18H20N4 |
| Molar Mass | 292.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Abd El-Aleam RH, et al. Design and synthesis of novel benzimidazole derivatives as potential Pseudomonas aeruginosa anti-biofilm agents inhibiting LasR: Evidence from comprehensive molecular dynamics simulation and in vitro investigation. Eur J Med Chem. |