| Bioactivity | LasR-IN-1 (compound 9g) is a potent LasR inhibitor. LasR-IN-1 has good efficacy toward E. coli. LasR-IN-1 shows anti-bacterial activity, with a MIC of 28.13 μM against P. aeruginosa[1]. |
| Invitro | LasR-IN-1 (compound 9g) inhibits the biofilm formation by over than 60.00%[1].LasR-IN-1 inhibits the pyocyanin production by over than 60.00%[1]. |
| Name | LasR-IN-1 |
| Formula | C23H21N3O2 |
| Molar Mass | 371.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Abd El-Aleam RH, et al. Design and synthesis of novel benzimidazole derivatives as potential Pseudomonas aeruginosa anti-biofilm agents inhibiting LasR: Evidence from comprehensive molecular dynamics simulation and in vitro investigation. Eur J Med Chem. |