| Bioactivity | Larazotideis a peptide which is an orally active zonulin antagonist. Larazotide shows antiviral activity to varicella-zoster virus (VZV) with EC50s of 44.14 and 59.06 μM for strain OKA and 07-1, respectively. Larazotide can be used for the research of celiac disease and infection[1][2]. |
| Invitro | Larazotide (1-100 μM; 5 d) affects Vero cell growth[1].Larazotide (1-100 μM; 3 d) shows antiviral activity to varicella-zoster virus (VZV) with EC50s of 44.14 and 59.06 μM for strain OKA and 07-1, respectively[1].Larazotide (1 and 3 mM; 72 h) inhibits cytokine-induced tight junction permeability in Caco-2 cells[2].Larazotide (100 μM; 3 h) inhibits gliadin translocation across Caco-2 monolayers[2].Larazotide (12.5 mM; 1 h) inhibits PTG-induced ZO-1 redistribution and actin cytoskeletal rearrangement in IEC6 cells[2]. Cell Cytotoxicity Assay[1] Cell Line: |
| Name | Larazotide |
| CAS | 258818-34-7 |
| Formula | C32H55N9O10 |
| Molar Mass | 725.83 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Larazotide
CAS: 258818-34-7 F: C32H55N9O10 W: 725.83
Larazotideis a peptide which is an orally active zonulin antagonist. Larazotide shows antiviral activity to varicella-zo
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