Bioactivity | Lansoprazole sulfide is an active metabolite of Lansoprazole by cytochrome P450, possesses anti-cancer activity. Lansoprazole sulfide is an anti-tuberculous agent, with an IC50 of 0.59 µM for M. tb[1]. | ||||||||||||
CAS | 103577-40-8 | ||||||||||||
Formula | C16H14F3N3OS | ||||||||||||
Molar Mass | 353.37 | ||||||||||||
Appearance | 固体 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Jenny Beebe, et al. Therapeutic Activity of the Lansoprazole Metabolite 5-Hydroxy Lansoprazole Sulfide in Triple-Negative Breast Cancer by Inhibiting the Enoyl Reductase of Fatty Acid Synthase. J Med Chem. 2022 Oct 27;65(20):13681-13691. [2]. Sipho Mdanda, et al. Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent. Biomed Chromatogr. 2017 Dec;31(12). |