| Bioactivity | Lansoprazole sulfide-d4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 µM intracellularly and 0.46 µM in broth[1]. | |||||||||
| Target | Proton pumpIC50: 0.59 µM (Mycobacterium tuberculosis intracellularly), 0.46 µM (Mycobacterium tuberculosis in broth) | |||||||||
| Name | Lansoprazole sulfide-d4 | |||||||||
| CAS | 1216682-38-0 | |||||||||
| Formula | C16H10D4F3N3OS | |||||||||
| Molar Mass | 357.39 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. Mdanda S, et al. Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent. Biomed Chromatogr. 2017 Dec;31(12). |