Bioactivity | Lanepitant (LY303870) is a selective neurokinin-1 (NK-1) receptor antagonist. Lanepitant blocks neurogenic inflammation and pain transmission by preventing the binding of substance P to NK-1 receptors on both neuronal and non-neuronal tissues. Lanepitant can be used to study osteoarthritis[1]. |
CAS | 170566-84-4 |
Formula | C33H45N5O3 |
Molar Mass | 559.74 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Goldstein D J, et al. Study of the analgesic effect of lanepitant in patients with osteoarthritis pain[J]. Clinical Pharmacology & Therapeutics, 2000, 67(4): 419-426. |