| Bioactivity | Lambertellin is an effective antibiotic that can be used as a bactericide and as a fungicide. Lambertellin exerts its anti-inflammatory effect in LPS (HY-D1056)-stimulated RAW 264.7 macrophage cells by modulating the activation of the MAPK and NF-κB signaling pathways[1]. |
| Invitro | 在脂多糖 (LPS) 刺激的 RAW 264.7 巨噬细胞中，Lambertellin 表现出抑制一氧化氮 (NO) 生成的良好活性，IC50 值为 3.19 µM，并且显著抑制诱导型 NO 合酶 (iNOS) 和环氧合酶 2 (COX-2) 的表达。Lambertellin 还会降低促炎细胞因子 IL-6 和 IL-1β[1] 的表达。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Lambertellin 相关抗体: |
| CAS | 28980-51-0 |
| Formula | C14H8O5 |
| Molar Mass | 256.21 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jean-Bosco Jouda, et al. Lambertellin from Pycnoporus sanguineus MUCL 51321 and its anti-inflammatory effect via modulation of MAPK and NF-κB signaling pathways. Bioorg Chem. 2018 Oct:80:216-222. |