| Bioactivity | LY43578 is an orally active aromatase inhibitor. LY43578 inhibits P-450-dependent p-nitroanisole O-demethylation and ethylmorphine N-demethylation in hepatic microsomes isolated from rat, with the IC50 of 0.3 and 5 μΜ, respectively. LY43578 can be used for neurological disorder study[1][2]. |
| Name | LY43578 |
| CAS | 26766-35-8 |
| Formula | C17H12Cl2N2O |
| Molar Mass | 331.20 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lindstrom TD, et al. Disposition of the aromatase inhibitor LY56110 and associated induction and inhibition studies in rats, dogs, and monkeys. Fundam Appl Toxicol. 1987;8(4):595-604. [2]. Gonzalez MI, et al. Injection of an aromatase inhibitor after the critical period of sexual differentiation. Pharmacol Biochem Behav. 1994;47(1):183-186. |