| Bioactivity | LY339434 is a potent and selective agonist for the hydrochloride receptor GluR5. LY339434 affects the rapid death of neurons through n-methyl-D-aspartate (NMDA) receptors[1][2]. |
| Invitro | LY339434 (1-1000 μM, 24 h) 浓度依赖性抑制小鼠皮质神经元细胞活力，EC50 为 11.4 μM[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> LY339434 相关抗体: |
| CAS | 219566-62-8 |
| Formula | C18H19NO4 |
| Molar Mass | 313.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Small B, et al. LY339434, a GluR5 kainate receptor agonist. Neuropharmacology. 1998 Oct-Nov;37(10-11):1261-7. [2]. Moldrich RX, et al. Excitotoxic profile of LY339434, a GluR5 agonist, in cultured murine cortical neurons. Brain Res. 2000 Apr 17;862(1-2):270-5. |