Bioactivity | LY3202626 is a CNS penetrant BACE inhibitor with IC50s of 0.615 nM and 0.871 nM against BACE1 and BACE2, respectively[1]. |
Target | IC50: 0.615 nM (BACE1), 0.871 nM (BACE2) |
Name | LY3202626 |
CAS | 1628690-73-2 |
Formula | C22H20F2N8O2S |
Molar Mass | 498.51 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. McKinzie DL, et al. Discovery and Early Clinical Development of LY3202626, a Low-Dose, CNS-Penetrant BACE Inhibitor. J Med Chem. 2021 Jun 24;64(12):8076-8100. |