PeptideDB

LY3202626

CAS: 1628690-73-2 F: C22H20F2N8O2S W: 498.51

LY3202626 is a CNS penetrant BACE inhibitor with IC50s of 0.615 nM and 0.871 nM against BACE1 and BACE2, respectively.
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity LY3202626 is a CNS penetrant BACE inhibitor with IC50s of 0.615 nM and 0.871 nM against BACE1 and BACE2, respectively[1].
Target IC50: 0.615 nM (BACE1), 0.871 nM (BACE2)
Name LY3202626
CAS 1628690-73-2
Formula C22H20F2N8O2S
Molar Mass 498.51
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. McKinzie DL, et al. Discovery and Early Clinical Development of LY3202626, a Low-Dose, CNS-Penetrant BACE Inhibitor. J Med Chem. 2021 Jun 24;64(12):8076-8100.