PeptideDB

LY2623091

CAS: 1162264-07-4 F: C30H30FN5O3 W: 527.59

LY2623091 is a mineralocorticoid receptor antagonist for the treatment of refractory hypertension. LY2623091 exhibits CY
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Bioactivity LY2623091 is a mineralocorticoid receptor antagonist for the treatment of refractory hypertension. LY2623091 exhibits CYP3A4-dependent clearance and synergistic effects with CYP3A4 inhibitors[1][2].
CAS 1162264-07-4
Formula C30H30FN5O3
Molar Mass 527.59
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Dickinson G L, et al. Physiologically based pharmacokinetic modeling to understand the observed drug–drug interaction of LY2623091 with CYP3A inhibitors itraconazole and diltiazem[J]. International journal of Pharmacokinetics, 2017, 2(4): 233-245. [2]. Kocienski P. Synthesis of LY2623091[J]. Synfacts, 2017, 13(05): 0451.