| Bioactivity | LY2023-001 is a potent G2019S LRRK2 inhibitor with an IC50 of 12.9 nM. LY2023-001 formed stable hydrogen bonds with Glu1948, and Ala1950 in the G2019S LRRK2 protein[1]. |
| CAS | 327031-30-1 |
| Formula | C19H18N6O3 |
| Molar Mass | 378.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shuoyan Tan, et al. Identification of novel LRRK2 inhibitors by structure-based virtual screening and alchemical free energy calculation. Phys Chem Chem Phys. 2024 Jul 24;26(29):19775-19786. |
LY2023-001
CAS: 327031-30-1 F: C19H18N6O3 W: 378.38
LY2023-001 is a potent G2019S LRRK2 inhibitor with an IC50 of 12.9 nM. LY2023-001 formed stable hydrogen bonds with Glu1
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