| Bioactivity | LY125180 is a serotonin uptake inhibitor. LY125180 competitively inhibits the uptake of serotonin and norepinephrine by cortical synaptosomes and of dopamine by striatal synaptosomes, with Ki values of 0.06 μM, 2.2 μM and 2.5 μM respectively[1]. |
| Name | LY125180 |
| CAS | 74515-39-2 |
| Formula | C18H24ClNO |
| Molar Mass | 305.84 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wong DT, et al. N,N-Dimethyl-alpha-[2-(p-tolyloxy)ethyl]benzylamine hydrochloride (LY125180). Effects on serotonin uptake and serotonin synthesis in rat brain in vitro and in vivo. Biochem Pharmacol. 1980 Mar 15;29(6):935-41. |