Bioactivity | LY 245769, a omega-trifluoro analog, is a leukotriene E4 (LTE4) inhibitor. LY 245769 interfers the omega-oxidation of N-acetyl-LTE4 and LTB4 with an IC50 of 4 μM[1]. |
CAS | 127345-02-2 |
Formula | C25H33F3N8OS |
Molar Mass | 550.64 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. G Jedlitschky, et al. Inhibition of leukotriene omega-oxidation by omega-trifluoro analogs of leukotrienes. Arch Biochem Biophys. 1990 Nov 1;282(2):333-9. |