| Bioactivity | LY 190388 is a penicillamine-containing enkefa peptide analog with μ receptor agonist activity. LY 190388 showed analgesic effect in inhibiting the writhing response in mice after intracerebroventricular administration. The analgesic effect of LY 190388 is not caused by its δ receptor agonist action, but by its μ receptor agonist activity. When LY 190388 is used together with the δ receptor antagonist ICI 174864, an additive analgesic effect is produced[1]. |
| CAS | 105496-35-3 |
| Sequence | Tyr-{d-Pen}-Gly-Phe-{d-Val} |
| Shortening | Y-{d-Pen}-GF-{d-Val} |
| Formula | C30H41N5O7S |
| Molar Mass | 615.74 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Comparison of two penicillamine-containing enkephalins: mu, not delta, activity produces analgesia |
LY 190388
CAS: 105496-35-3 F: C30H41N5O7S W: 615.74
LY 190388 is a penicillamine-containing enkefa peptide analog with μ receptor agonist activity. LY 190388 showed analge
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