Bioactivity | LXR (Liver X receptor) agonist 1 is potent LXR agonist with AC50s of 1.5 nM and 12 nM for LXR-α and LXR-β, respectively. LXR agonist 1 has the potential for the research of atherosclerosis[1]. |
Target | AC50: 1.5 nM (LXR-α); 12 nM (LXR-β) |
Invitro | LXR agonist 1 (compound 3) shows binding affinities with AC50s of 1.5 nM and 12 nM for LXR-α and LXR-β, respectively[1]. |
Name | LXR agonist 1 |
CAS | 1779524-90-1 |
Formula | C27H26F3N3O3S |
Molar Mass | 529.57 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Lim RK, et al. Targeted Delivery of LXR Agonist Using a Site-Specific Antibody-Drug Conjugate. Bioconjug Chem. 2015; 26(11):2216-22. |