Bioactivity | LUF7346 is a potent Kv11.1 (hERG) channel negative allosteric modulator, with an IC50 of 35.6 ± 3.2 nM[1]. |
Name | LUF7346 |
CAS | 1821638-40-7 |
Formula | C20H15BrN2O3 |
Molar Mass | 411.25 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. van Veldhoven JPD, et al. Targeting the Kv11.1 (hERG) channel with allosteric modulators. Synthesis and biological evaluation of three novel series of LUF7346 derivatives. Eur J Med Chem. 2021 Feb 15;212:113033. |