PeptideDB

LUF7346

CAS: 1821638-40-7 F: C20H15BrN2O3 W: 411.25

LUF7346 is a potent Kv11.1 (hERG) channel negative allosteric modulator, with an IC50 of 35.6 ± 3.2 nM.
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Bioactivity LUF7346 is a potent Kv11.1 (hERG) channel negative allosteric modulator, with an IC50 of 35.6 ± 3.2 nM[1].
Name LUF7346
CAS 1821638-40-7
Formula C20H15BrN2O3
Molar Mass 411.25
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. van Veldhoven JPD, et al. Targeting the Kv11.1 (hERG) channel with allosteric modulators. Synthesis and biological evaluation of three novel series of LUF7346 derivatives. Eur J Med Chem. 2021 Feb 15;212:113033.